The concert, which marks the final performance in the space on West 22nd Street before the theatre begins its renovation, will feature Kerry Conte, Patrick Cummings, Danielle Ferland, Beth Fowler, Bonnie Fraser, Jessica Grove, Rita Harvey, Kristin Huxhold, Mary Illes, Elizabeth Inghram, Donna Kane, Chad Kimball, Kerry O'Malley, Jenny Powers, Ciaran Sheehan, David Staller and Max Von Essen in performance.
"On this night, just days before the arrival of the wrecking ball, we will raise a glass and sing the songs that have rocked these walls," artistic director Charlotte Moore said in a statement.
A reception with the cast, crew and staff of the Irish Rep will follow the concert.
Arranged by Moore, Meet Me at the Square will feature music direction by John Bell and Mark Hartman.
Mioi Takeda (violin), Melanie Mason (cello), Jeremy Clayton (woodwinds) and Joy Plaisted (harp) comprise the band. Beginning Sept. 24, The Irish Repertory Theatre will be in residence at the DR2 Theatre in Union Square
The Irish Repertory Theatre is located at 132 West 22nd Street. Tickets and more information are available by calling (212) 255-0270 or visiting IrishRep.org.